Eli C. D. Shortridge spent formative years in various locations, including Cabell County, Virginia (now West Virginia), Monroe County, Missouri, and Larimore, Dakota Territory. He completed his education at an academy near Paris, Missouri. Shortridge transitioned from a private sector background to a political career, culminating in his election as governor on a fusion ticket of Populists, Democrats, and the Farmers' Alliance. During his tenure, he approved significant state infrastructure investments, including bonds for the state capitol and the purchase of an executive mansion. Post-governorship, he served as clerk of the United States General Land Office at Devils Lake, North Dakota.

Eli C. D. Shortridge's political identity is marked by an ideologically agile approach, blending Populist and Democratic principles to form the Democratic-Independent Party. His tenure as governor saw him approve significant state infrastructure investments, yet his support for a state elevator in Duluth, despite sovereignty issues, highlights a strategic focus on regional economic interests. Shortridge's rhetorical style likely emphasizes localized benefits and pragmatic investments, though the full extent of his calculated approach remains intriguing.