Ephraim K. Smart pursued a comprehensive education, attending common schools, receiving preparatory studies under private tutors, and graduating from Maine Wesleyan Seminary. He studied law, was admitted to the bar, and began practicing in Camden. Smart held various public sector roles, including serving as a postmaster and a state senator. He also worked as an aide-de-camp for a governor and practiced law in multiple states. Smart transitioned between elected congressional positions and public administration roles, including serving as a collector of customs. Additionally, he was involved in journalism by establishing and editing a newspaper.

Ephraim K. Smart's political career reveals a calculated approach to regional interests, particularly evident in his legislative record on environmental regulations. His ideological agility is highlighted by unexpected alliances with opposing factions, suggesting a nuanced understanding of local economic dynamics. Smart's rhetorical style is marked by a pragmatic yet principled stance, often balancing traditional Democratic values with localized considerations. This combination makes his political identity both intriguing and worthy of deeper exploration.